MicrobiologybioRxivPreprint
TXA11114: Discovery of an in vivo efficacious efflux pump inhibitor in Pseudomonas aeruginosa
Jesús D. Rosado-Lugo, Pratik Datta, Ahmad S. Altiti…·Ajit K Parhi
This paper describes the discovery of TXA11114, an efflux pump inhibitor that enhances levofloxacin efficacy against multidrug-resistant Pseudomonas aeruginosa in vivo with a safe toxicology profile.
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