Author

Zachery Keepers

University of Maryland, BaltimoreORCID 0009-0008-8730-5435Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Chayu YangiD· 1 shared Hem Dutt ShuklaiD· 1 shared Lei ReniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Chayu YangORCID

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1 paper

Recent·Most cited

Cancer BiologyRadiotherapy and OncologyPeer-reviewedMar 4, 2026

Tumor Organoids Modeling Reveals Timed Responses and Interplay of Radiotherapy and Chemotherapy in Pancreatic Cancer

Chayu Yang, Zachery Keepers, Hem Dutt Shukla, Lei Ren

This study models the therapeutic effects of chemotherapy, radiotherapy, and their combination on patient-derived tumor organoids using mathematical frameworks, revealing heterogeneous treatment responses and synergistic interactions.

DOI 10.1016/j.radonc.2026.111470

humanorganoid / primary culture

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