Lisa Chang

This study shows that disrupting NMDA receptor-mediated glutamatergic input to ALDH1A1+ dopaminergic neurons causes sex-specific feeding abnormalities linked to Parkinson's disease.

This study investigates the functional roles of two nigrostriatal dopaminergic neuron subtypes in motor and associative learning using genetic and chemogenetic approaches in mice.

This study identifies a subtype of striatonigral neurons that modulate locomotor speed based on environmental valence in mice.

This study identifies a subtype of striatonigral neurons that regulate locomotion speed based on environmental valence through genetic and optogenetic manipulations in mice.

The paper investigates how striosomes influence locomotor speed based on contextual valence using ablation, calcium imaging, and chemogenetics in a modified Light/Dark box test.

This study shows that deficiency in DAGLB, an endocannabinoid synthase, contributes to Parkinson's disease by impairing dopaminergic neuron function and motor learning, with potential therapeutic implications for 2-AG augmentation.