Cell BiologybioRxivPreprint
TSC1 phosphorylation by lysosomal mTORC1 establishes a minimal autoregulatory feedback loop
Andreas A. Lamprakis, Constantinos Demetriades
This study identifies TSC1 as a direct mTORC1 substrate, revealing a minimal autoregulatory feedback loop that selectively controls lysosomal mTORC1 signaling.
DOI 10.64898/2026.01.15.699678