Author

Samuel Egan

Royal College of Surgeons in IrelandORCID 0009-0008-9212-2529Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Bilal El‐MansouryiD· 2 shared David Clifford HenshalliD· 2 shared Jordan HigginsiD· 2 shared Omar MamadiD· 2 shared Albert SanfeliuiD· 1 shared Javier Villegas-SalmeróniD· 1 shared Keelin HarrisoniD· 1 shared Mona HeilandiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersNeuroscience

Bilal El‐MansouryORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 24, 2026

CDKL5 deficiency alters cell subtype-specific molecular programmes and intercellular signalling in the mouse hippocampus

Javier Villegas-Salmerón, Samuel Egan, Albert Sanfeliu…·Omar Mamad

This study uses snRNA-seq to analyze gene expression changes in the hippocampus of CDKL5-deficient mice, identifying cell-type-specific transcriptional alterations and intercellular signaling changes.

DOI 10.64898/2026.10.22.760890

mousescRNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintAug 7, 2026

VECTR-Clasp: An open machine-learning and vector-based framework for objective quantification of motor dysfunction during hind-limb clasping in Cdkl5-deficient mice

J. S. Higgins, Samuel Egan, Keelin Harrison…·Omar Mamad

VECTR-Clasp provides a continuous geometric analysis of motor behavior in Cdkl5-deficient mice, revealing previously undetected motor microphenotypes.

DOI 10.64898/2026.02.25.707643

mouseimaging

𝕏 PostBluesky