MicrobiologybioRxiv
Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach
Nisheeth Agarwal, Himanshu Gogoi, Eeba Eeba…·Bappaditya Dey
This study identifies a novel L-leucine uptake mechanism in Mtb using a chemical genomic approach, revealing a target involved in cell-wall lipid biosynthesis and demonstrating in vivo efficacy of semapimod.
DOI 10.7554/elife.107025