Yashwant Kumar

This study shows that the direct sulfhydrylation pathway in Mycobacterium tuberculosis is essential for growth at low pH and modulates BDQ sensitivity.

This study identifies a novel L-leucine uptake mechanism in Mtb using a chemical genomic approach, revealing a target involved in cell-wall lipid biosynthesis and demonstrating in vivo efficacy of semapimod.

This study shows that (p)ppGpp and DksA reduce the effectiveness of beta-lactam antibiotics by altering bacterial membrane permeability and peptidoglycan biosynthesis in Vibrio cholerae.

IDSL.CSA generates composite mass spectra libraries from MS1-only data to annotate untargeted metabolomics datasets without MS2 fragmentation spectra, achieving comparable results to MS/MS libraries in human blood samples.

IDSL.UFA annotates molecular formulas for untargeted LC/HRMS data, achieving high accuracy in metabolomics and exposomics studies.