NeurosciencebioRxivPreprint
Quantitative study of alpha-synuclein prion-like spreading in fully oriented reconstructed neural networks reveals non-synaptic dissemination of seeding aggregates
Josquin Courte, Ngoc Anh Le, Luc Bousset…·Jean‐Michel Peyrin
This study uses a novel microfluidic system to investigate how alpha-synuclein aggregates spread between neurons, finding that synaptic connectivity does not significantly affect transfer efficiency.
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