Author

Yao Xiao

University of Southern CaliforniaORCID 0009-0009-3361-1303Unclaimed ORCID profile · follow to get notified of new preprints

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Yao Xiao1 paper · Peking University

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Assay:imaging· 1

Frequent Co-Authors

Geoffrey FudenbergiD· 2 shared Hadi RahmaninejadiD· 2 shared Elphège Pierre NoraiD· 1 shared Erika C. AndersoniD· 1 shared Maxime M. C. TortoraiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

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5 top collaborators · 8 mutual co-author links

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2 shared papersGenomics

Geoffrey FudenbergORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 25, 2026

Antibody background in ChIP-seq skews estimates of cohesin positioning by CTCF barriers

Yao Xiao, Erika C. Anderson, Hadi Rahmaninejad…·Geoffrey Fudenberg

The paper develops a framework to correct cohesin positioning measurements in ChIP-seq by accounting for antibody background, revealing its impact on cohesin positioning estimates.

DOI 10.64898/2026.02.26.708306

𝕏 PostBluesky

GenomicsGenome ResearchPeer-reviewedAug 1, 2025

Dynamic barriers modulate cohesin positioning and genome folding at fixed occupancy

Hadi Rahmaninejad, Yao Xiao, Maxime M. C. Tortora, Geoffrey Fudenberg

The paper develops a dynamic barrier model to explain genome folding features using biophysically measured CTCF and cohesin dynamics, showing that barrier bound times influence ChIP-seq, Hi-C, and chromosome morphology.

8 citations

𝕏 PostBluesky