Author

Dinja van der Hoorn

Leiden University Medical CenterORCID 0009-0009-3509-0281Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

Adam K. WalkeriD· 1 shared Alexandra D. GurzauiD· 1 shared Andrés Tapia del FierroiD· 1 shared Andrew KeniryiD· 1 shared Anna McFarlaneiD· 1 shared Anna Sanchez Avila· 1 shared Bianca den Hamer· 1 shared Bruno ReversadeiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adam K. WalkerORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 25, 2026

Breakdown in the synaptic vesicle cycle defines early and reversible cortical pathogenesis in ALS

Zsófia I. László, Anna Sanchez Avila, Anna McFarlane…·Christopher M. Henstridge

The paper identifies early synaptic vesicle cycle disruption in ALS using proteomics and shows it is reversible with TDP-43 suppression.

DOI 10.64898/2026.08.21.746168

humanproteomics

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedSep 25, 2023

SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease

Andrés Tapia del Fierro, Bianca den Hamer, Natalia Benetti…·Marnie E. Blewitt

This study identifies a mutation in SMCHD1 that enhances gene silencing and disrupts developmental processes, revealing distinct roles of SMCHD1 in chromatin structure and gene regulation.

26 citations

𝕏 PostBluesky