Author

Amarin Wongariyapak

Institute of Cancer ResearchORCID 0009-0009-3867-1022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alan A. MelcheriD· 2 shared Antonio RullaniD· 2 shared Charleen Chan Wah HakiD· 2 shared Elizabeth S. AppletoniD· 2 shared Emmanuel Christian PatiniD· 2 shared Joan KyulaiD· 2 shared Kevin Joseph HarringtoniD· 2 shared Malin PederseniD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alan A. MelcherORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 29, 2026

Intratumoural oncolytic HSV-1 reshapes the local and systemic immune landscape through CD8+ T cell reprogramming

Elizabeth S. Appleton, Anton Patrikeev, Victoria Roulstone…·Alan A. Melcher

This paper shows that intratumoural oncolytic HSV-1 reprograms systemic immunity by inducing specific CD8 T cell populations that correlate with clinical response to immunotherapy.

DOI 10.64898/2026.04.07.716986

mousebulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedJul 8, 2025

PARP inhibitors enhance reovirus-mediated cell killing through the death-inducing signaling complex (DISC) with an associated NF-kappa B-regulated immune response.

Joan Kyula, Victoria Roulstone, James Wright…·Kevin Joseph Harrington

This paper identifies PARP inhibitors as sensitizers for oncolytic reovirus by enhancing DISC-mediated apoptosis and NF-kappa B-driven immune responses.

10 citations

humanmouse

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