Author

Alex Engel

Stanford UniversityORCID 0009-0009-4361-7282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alice FinkelsteiniD· 1 shared Amanuel Worku GeremewiD· 1 shared Ayushi MohantyiD· 1 shared Heloise M. HoffmanniD· 1 shared Katherine XuiD· 1 shared María Fernanda VelásqueziD· 1 shared Michael LiuiD· 1 shared Phillip KyriakakisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Alice FinkelsteinORCID

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintAug 20, 2026

In vitro and in silico characterization of competitive inhibition and repression of DUX4 target gene activation as a therapeutic approach for facioscapulohumeral muscular dystrophy (FSHD)

Heloise M. Hoffmann, Alice Finkelstein, Amanuel Worku Geremew…·Phillip Kyriakakis

This paper demonstrates that a DUX4 DNA-binding domain fused to a human KRAB domain can effectively repress DUX4-FL transcriptional activity in vitro, and develops computational models to explore its therapeutic potential for FSHD.

DOI 10.64898/2026.08.04.742607

humanproteomics

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