Author

Amanuel Worku Geremew

Stanford UniversityORCID 0009-0009-9979-2151Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Phillip KyriakakisiD· 2 shared Alex EngeliD· 1 shared Alexandre W. Bisson FilhoiD· 1 shared Alice FinkelsteiniD· 1 shared Ayushi MohantyiD· 1 shared Heloise M. HoffmanniD· 1 shared John P. MalloniD· 1 shared Katherine XuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

Phillip KyriakakisORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 30, 2026

OpenEvo: An Open-Source Platform for Automated Evolution and Analysis

Sebastian S. Cocioba Sebastian S. Cocioba, Pin-Che Huang, John P. Mallon…·Phillip Kyriakakis

OpenEvo is an open-source platform for automated evolution experiments that enables directed evolution with cost-effective, user-friendly hardware and software.

DOI 10.64898/2026.07.06.735356

experimental assay

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BioengineeringbioRxivPreprintAug 20, 2026

In vitro and in silico characterization of competitive inhibition and repression of DUX4 target gene activation as a therapeutic approach for facioscapulohumeral muscular dystrophy (FSHD)

Heloise M. Hoffmann, Alice Finkelstein, Amanuel Worku Geremew…·Phillip Kyriakakis

This paper demonstrates that a DUX4 DNA-binding domain fused to a human KRAB domain can effectively repress DUX4-FL transcriptional activity in vitro, and develops computational models to explore its therapeutic potential for FSHD.

DOI 10.64898/2026.08.04.742607

humanproteomics

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