Nathan Paul

This paper introduces genetically encoded benzodiazole-based probes for quantitative FLIM, enabling site-specific analysis of protein microenvironments in living cells.

The paper designs lanthanide-binding mini-proteins with enhanced luminescence using non-canonical amino acids and computational methods.

This paper introduces 4-cyano-tryptophan (4-CN-Trp) as a fluorescent amino acid that preserves protein structure and enables detection of ligand binding sites through fluorescence changes.