Haocheng Qianzhu

This paper introduces genetically encoded benzodiazole-based probes for quantitative FLIM, enabling site-specific analysis of protein microenvironments in living cells.

This paper introduces azatryptophans to engineer enzymes with enhanced activity and preserved stability, demonstrating their effectiveness in PETase optimization.

The paper designs lanthanide-binding mini-proteins with enhanced luminescence using non-canonical amino acids and computational methods.

This paper introduces 4-cyano-tryptophan (4-CN-Trp) as a fluorescent amino acid that preserves protein structure and enables detection of ligand binding sites through fluorescence changes.