BiochemistryAngewandte Chemie International EditionPeer-reviewed
Rendering Proteins Fluorescent Inconspicuously: Genetically Encoded 4-Cyanotryptophan Conserves Their Structure and Enables the Detection of Ligand Binding Sites
Haocheng Qianzhu, Elwy H. Abdelkader, Adarshi P. Welegedara…·Gottfried Otting
This paper introduces 4-cyano-tryptophan (4-CN-Trp) as a fluorescent amino acid that preserves protein structure and enables detection of ligand binding sites through fluorescence changes.
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