Author

Matthew B. Jacobo

University of Southern CaliforniaORCID 0009-0009-7651-7069Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Aaron G. BaughiD· 2 shared Adam L. MacLeaniD· 2 shared Batul Al-ZubeidyiD· 2 shared Edgar Gonzalez· 2 shared Evanthia T. Roussos TorresiD· 2 shared Jesse KregeriD· 2 shared Yingtong LiuiD· 2 shared Alex LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersImmunology

Aaron G. BaughORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 25, 2026

A class act: HDAC1-Malat1 regulates MDSC apoptosis and cell cycling to decrease suppression of T cells

Aaron G. Baugh, Yingtong Liu, Edgar Gonzalez…·Evanthia T. Roussos Torres

The paper shows HDAC1 inhibition in MDSCs increases Malat1, decreases pSTAT3, induces apoptosis and cell cycle arrest, and reduces T cell suppression.

2 citations

humanmouse

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Cancer BiologybioRxivPreprintJun 9, 2025

Cancer systems immunology reveals myeloid - T cell interactions and B cell activation mediate response to checkpoint inhibition in metastatic breast cancer

Edgar Gonzalez, Jesse Kreger, Yingtong Liu…·Evanthia T. Roussos Torres

The paper investigates how myeloid-T cell interactions and B cell activation influence response to checkpoint inhibition in metastatic breast cancer using multi-omics and computational methods.

DOI 10.1101/2025.06.09.658361

humanscRNA-seq

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