Peyton McClelland

This study uses Mendelian randomization to identify circulating proteins associated with cardiovascular traits in African-ancestry populations and finds four proteins uniquely linked to lipids and heart diseases in this group.

The paper constructs a genetic reference panel for the Quebec population using whole-genome sequencing and GWAS to improve phenotype-genotype association discovery.

WEGS combines low-depth whole genome and high-depth whole exome sequencing to reduce costs while maintaining variant detection accuracy in genetic studies.