Integrating Fas-mediated apoptosis with IFNγ signaling to drive tumor regression in mRNA cancer therapeutics
Hee-su Shin, Soon-Gyu Kwon, Hayyoung Lee, Jie‐Oh Lee
This paper develops an mRNA-based therapy combining IFNγ and FasICD to induce tumor cell death and immune activation, showing significant tumor regression in mice.
bioRxiv · Apr 8, 2026 · PreprintCancer Biology