NeurosciencebioRxivPreprint
Conserved microglial programmes, non-transferable classifiers: boundaries of the single-cell TBI molecular clock
Yan Qi, Zhang Li, Li Zhang…·Yingshu Zhang
This paper evaluates the transferability of a single-cell molecular clock for traumatic brain injury (TBI) staging across datasets, finding poor cross-dataset generalization and identifying a conserved microglial gene-expression programme as the reproducible component.