Author

Ismaïl Hermelo

Tampere UniversityORCID 0009-0009-9381-839XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Matti NykteriD· 3 shared Aliisa M. TiihoneniD· 2 shared Iida SaloneniD· 2 shared Kirsi J. RautajokiiD· 2 shared Abhibhav SharmaiD· 1 shared Alexander GieseniD· 1 shared Alfonso UrbanucciiD· 1 shared Alli Leppä· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Matti NykterORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 11, 2026

Multi-region whole-genome and transcriptomic profiling uncovers plastic, subclone-linked cell states in high-grade diffuse astrocytomas

Serafiina Ohlsbom, S Mäntylä, Reetta Nätkin…·Matti Nykter

This study uses multi-region whole-genome and transcriptomic profiling to show how genomic backbones and regional transcriptional plasticity drive phenotypic diversity in high-grade astrocytomas.

DOI 10.64898/2026.08.11.743949

humanwhole-genome sequencing

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Cancer BiologybioRxivPreprintMar 24, 2025

Sustained epithelial interferon signaling modulates incomplete pathologic response in colorectal cancer

Erdoğan Pekcan Erkan, Emmi Hämäläinen, Julia Kolikova…·Toni T. Seppälä

This study identifies interferon signaling in epithelial cells as a factor contributing to incomplete response to chemotherapy in colorectal cancer, suggesting potential therapeutic targets.

DOI 10.1101/2025.03.24.644737

humanbulk RNA-seq

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Cancer BiologyNature CommunicationsPeer-reviewedNov 16, 2024

Immunosuppression in the prostate tumor microenvironment is tied to androgen deprivation therapy-resistant club-like cells

Antti Kiviaho, Sini K. Eerola, Heini M. L. Kallio…·Matti Nykter

The paper identifies club-like cells in the prostate tumor microenvironment that contribute to androgen deprivation therapy resistance through immune suppression.

104 citationstop 1%

humanscRNA-seq

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