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BioinformaticsbioRxiv
Preprint

WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling

Zewei SongiD, Xiaohuan SuniD, Zhongkui XiaiD, Yangyang JiaiD, Zhu Jie, Chao FangiD, Huanming YangiD, jian Zi WangiD

Abstract

Amplicon sequencing need to go from using single region to multiple region, one for higher resolution, one for technical replicates. WinnerTakeAlmostAll is an algorithm to calculate a minimum set of references based on the reference-query graph. We showed that this algorithm is superior in resolving species, as well as average out the run effect using technical replicates.

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02 /Specification & Classification

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