bioRxivNeurosciencePreprint
Ultraslow entorhinal oscillations shape spatial memory through grid cell drifting
Abstract
ContextGrid cells in the medial entorhinal cortex (MEC) of head-fixed mice exhibit ultraslow (DiscussionsUltraslow entorhinal oscillations were found to shape spatial memory through grid cell drifting, which could serve as a mechanism for flexibly accessing different spatial memories during navigation. HIGHLIGHTSO_LIPath integration dynamics hide ultraslow oscillations despite coexistence. C_LIO_LIUltraslow oscillations significantly degrade position estimation in path integration. C_LIO_LIGrid and place fields drift after the effect of ultraslow oscillations. C_LIO_LINew spatial memories were created as a result of the ultraslow oscillation drift. C_LIO_LIUltraslow oscillations enable dynamic access of different spatial memories C_LI
- organism: mouse
- assay: electronic health records
- research focus: spatial domain detection
- approach: experimental assay
- Citations
- 0
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Minute-scale oscillatory sequences in medial entorhinal cortex
Soledad Gonzalo Cogno, Horst Andreas Obenhaus, … Edvard Ingjald Moser·bioRxiv·May 2, 2022
- A consistent map in the medial entorhinal cortex supports spatial memory
Taylor Joseph Malone, Nai-Wen Tien, … Yi Zhuo Gu·Nature CommunicationsPeer-reviewed·Feb 17, 2024
- Grid cells encode reward distance during path integration in cue-rich environments
Satoshi Kuroki, Sébastien Royer·bioRxiv·Sep 3, 2025
- Spatial and temporal representations are organized along a stable coding gradient in the medial entorhinal cortex
Hyun‐Woo Lee, John C. Bowler, James G. Heys·bioRxiv·Jul 10, 2026
- Medial septum glutamatergic neurons support speed coding and grid cell spatial stability in the medial entorhinal cortex
Jennifer C. Robinson, James Eric Carmichael, … Michael Erik Hasselmo·bioRxiv·Sep 30, 2026
- Effects of visual inputs on neural dynamics for coding of location and running speed in medial entorhinal cortex.
Holger Dannenberg, Hallie Lazaro, … Michael Erik Hasselmo·eLifePeer-reviewed·Dec 10, 2020