Identification of a Novel SARS-CoV-2 Delta-Omicron Recombinant Virus in the United States
Kristine A. LacekiD, Benjamin L. Rambo‐MartiniD, Dhwani Govil BatraiD, Xiao-yu Zheng, Hitoshi Sakaguchi, Thomas P. PeacockiD, Matthew W. KelleriD, Malania M. WilsoniD, Mili ShethiD, Morgan L. Davis, Mark Borroughs, Jonathan Gerhart, Norman HasselliD, Samuel S. ShepardiD, Peter W. CookiD, Justin LeeiD, David E. WentworthiD, John BarnesiD, Rebecca J Garten KondoriD, Clinton R. PadeniD
Abstract
Recombination between SARS-CoV-2 virus variants can result in different viral properties (e.g., infectiousness or pathogenicity). In this report, we describe viruses with recombinant genomes containing signature mutations from Delta and Omicron variants. These genomes are the first evidence for a Delta-Omicron hybrid Spike protein in the United States.
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