Saumitra Das

IRES-mediated translation of delta160p53 regulates p53 functions and fine-tunes cancer homeostasis

The paper investigates IRES-mediated translation of delta160p53 and shows it promotes cancer cell survival and drug resistance by altering cell cycle and apoptosis.

Viral Protease Nsp5 Hijacks La Autoantigen to Orchestrate the Translation to Replication Transition in SARS-CoV-2

This paper shows that SARS-CoV-2's Nsp5 protease cleaves La protein to switch viral RNA from translation to replication.

Interaction and co-phase separation of SARS-CoV-2 nucleocapsid protein and human hnRNPA1 and its implications for viral life cycle

This study investigates the interaction between SARS-CoV-2 N protein and hnRNPA1, showing their physical binding and phase separation, and highlights hnRNPA1's role in suppressing viral replication.

RB1 gene mutations and their association with Endometrial Cancer

The paper investigates RB1 mutations in endometrial cancer, finding higher prevalence in younger patients and linking RB1 mutations to HPV infection pathways.

Dual role of Human antigen R in Dengue virus infection: suppression of replication and promotion of cap-independent translation

This study identifies HuR as a dual regulator of DENV infection, suppressing replication early and promoting cap-independent translation later.

microRNA-22 displaces ITAFs from the 5'UTR and inhibit the translation of Coxsackievirus B3 RNA

This study shows miR-22 binds to CVB3 5'UTR, displaces ITAFs, inhibits translation, and reduces viral infection.

Delta40p53 plays a distinct regulatory role in maintaining cellular homeostasis by controlling SGSH expression via miR-4651-5p

The paper identifies a novel regulatory axis involving Delta40p53, miR-4671-5p, and SGSH that influences cell cycle progression and cancer outcomes.

Evolution of Delta variant by non-Spike signature co-appearing mutations: trailblazer of COVID-19 disease outcome

The paper identifies non-Spike mutations in Delta variant SARS-CoV-2 that correlate with symptomatic and asymptomatic infections and suggests their potential role in future vaccine-evading variants.

PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Reveals Important Insights into the Outbreak

The paper sequences 1000 SARS-CoV-2 genomes from India, revealing multiple circulating lineages, predominant A2a haplotype with D614G mutation, and geographic mutation clustering.