DNAlogo: a smart mini application for generating DNA sequence logos

Abstract

Sequence logos are frequently used for presenting consensus sequences and motifs of nucleic acids and proteins. WebLogo of UC Berkeley is the most popular tool for creating sequence logos, whereas, it is often restricted by the internet speed in some developing countries and no graphic interface for its stand-alone version. Here, the author generated an application, DNAlogo, using VB.net, which runs in Windows system. DNAlogo is small and convenient. It creates both bitmap and vector map. Beside the classic sequence logo function, DNAlogo introduced compensated logo to generate consensus sequences considering different GC contents of different genomes. DNAlogo provides a simple way for researchers without programming knowledge to create DNA sequence logos.