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Pharmacology & ToxicologybioRxiv
Preprint

Rapid Peripheral Disintegration of Planaria in the Presence of Barium

A. Molano

Abstract

Bioelectric signalling has been implicated in planaria regeneration and anatomical homeostasis. Previous reports demonstrated that barium chloride (1 mM), a potassium channel blocker, produced slow disintegration of the head (in 72 hours) in a clonal strain of Dugesia japonica. To investigate whether the effects of barium were similar in all planaria species, I tested its effects in wild Girardia sp. collected from a stream. The results were significantly different from those seen in Dugesia japonica: At 1 mM, these worms underwent complete peripheral disintegration within thirty minutes.

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