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GARDEN-NET and ChAseR: a suite of tools for the analysis of chromatin networks

Miguel Madrid-MencíaiD, Emanuele RaineriiD, Véra PancaldiiD

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Abstract

We introduce an R package and a web-based visualization tool for the representation, analysis and integration of epigenomic data in the context of 3D chromatin interaction networks. GARDEN-NET allows for the projection of user-submitted genomic features on pre-loaded chromatin interaction networks exploiting the functionalities of the ChAseR package to explore the features in combination with chromatin network topology. We demonstrate the approach on epigenomic and chromatin structure datasets in haematopoietic cells.

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