Weiqun Peng

This study identifies PRMT1-SFPQ as a regulator of intron retention in craniofacial development, leading to reduced matrix gene expression through NMD.

This study shows ISWI remodelers are essential for muscle and adipose development and link LDTF binding to cBAF recruitment during cell fate transition.

The paper shows that chromatin modifiers KMT2D, BAF, and p300 are required for de novo TF binding on enhancers, revealing cooperative interactions rather than a strict hierarchy.

This study shows that MLL3/MLL4 methyltransferase activities are essential for early embryonic development and stem cell differentiation, but their role is lineage-selective and not dependent on enhancer activation.

HiCHub identifies domains of differential chromatin interactions from 3D genome data by detecting clusters of genomic elements with concurrent interaction changes and state concordance.

This study shows BAF and MLL4 work together to activate cell type-specific enhancers during adipogenesis, with BAF being essential for differentiation while PBAF is not.

This paper introduces Lollipop, a machine-learning framework that predicts CTCF-mediated chromatin interactions using genomic and epigenomic features, outperforming existing methods.