BMC BioinformaticsBioinformaticsPeer-reviewed journal article
Vertical and horizontal integration of multi-omics data with miodin
Abstract
SummaryStudies on multiple modalities of omics data such as transcriptomics, genomics and proteomics are growing in popularity, since they allow us to investigate complex mechanisms across molecular layers. Integration of multi-omics data remains challenging and requires combination of several software tools to process data and generate biological insights. This paper presents miodin, a software package for streamlined data analysis and integration of omics data across experiments on the same samples, or across studies on the same variables.\n\nAvailability and implementationThe miodin package is implemented in R and is freely available for use and extension under the GPL-3 license. Package source, reference documentation and user manual are available at https://gitlab.com/algoromics/miodin.\n\nContactbenjamin.ulfenborg@his.se
- assay: bulk RNA-seq
- assay: proteomics
- assay: DNA methylation
- research focus: batch correction / integration
- research focus: benchmarking
- research focus: database / resource
- approach: statistical model
- approach: machine learning (classical)
- Citations
- 73
- FWCI
- 3.64
- Field percentile
- top 5%
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