bioRxivEvolutionary BiologyPreprint
Aevol-9: A simulation platform to decipher the evolution of genome architecture
Juliette LuiselliiD, David P. ParsonsiD, R R GalleiD, Paul BanseiD, Jonathan Rouzaud-CornabasiD, Guillaume BesloniD
Abstract
Aevol is a forward-in-time simulator of genome architecture. It simulates a population of individuals, each with an explicit genome whose sequence and architecture can be modified by various mutational operators, including substitutions, indels, and large-scale chromosomal rearrangements. This enables performing in silico experiments to decipher the effects of evolutionary conditions (e.g. population size, selection strength, mutation rates, and biases) on genome organization.
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