Guillaume Beslon

The paper distinguishes mutational robustness from replicative robustness, showing they can be selected in opposite directions and highlighting the importance of replication event dynamics in evolutionary robustness.

The paper proposes a mathematical model showing how genome size evolution is shaped by mutation biases and robustness selection, leading to an equilibrium non-coding fraction.

This study shows that DNA supercoiling-mediated interactions between genes can shape genome organization and regulate gene expression through evolutionary adaptation.

This paper uses in silico evolution to study how pleiotropy affects genetic and phenotypic evolution, finding that it accelerates genetic divergence and promotes fitness improvements.

Aevol-9 simulates genome architecture evolution through mutational operators to study how evolutionary conditions affect genome organization.

This study uses computational models to show that population size and mutation rate interact to determine genome size and coding density in bacteria.