Mobile DNABioinformaticsPeer-reviewed journal article
TE-Seq: A Transposable Element Annotation and RNA-Seq Pipeline
Maxfield M. G. KelseyiD, Radha L. KalekariD, John M. SedivyiD
Abstract
The recognition that transposable elements (TEs) play important roles in many biological processes has elicited growing interest in analyzing sequencing data derived from this mobile dark genome. The TE-Seq pipeline conducts an end-to-end analysis of RNA-sequencing data, examining both genes and TEs. It implements the most current computational methods tailor-made for TEs, enabling a comprehensive analysis of TE expression at both the individual element level and at the TE clade level. If supplied with long-read DNA sequencing data, it creates a TE-complete genome incorporating non-reference (polymorphic) TE-loci, enabling the functional characterization of the evolutionarily youngest mobile elements in the genome.
- assay: bulk RNA-seq
- assay: long-read sequencing
- research focus: gene regulatory network inference
- research focus: variant calling
- approach: statistical model
- Citations
- 10
- FWCI
- 5.40
- Field percentile
- top 4%
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