bioRxivMicrobiologyPreprint
Identifying Plasmids in Bacterial Genome Assemblies
Abstract
Despite their importance to bacterial pathogenesis, plasmids are rarely identified in incomplete genome sequences. The free FindPlasmids (FP) package for Windows, Mac OS X, and Linux facilitates identification of plasmids in incomplete genome sequences. FP found plasmids in 98.8% of complete genomes in which they were present, correctly identifying plasmids ranging in number from 1 to 10 plasmids. In a sample of 50 E. coli genome assemblies it has identified from zero to three plasmids ranging in size from 1,549 to 133,843 bp and present in 42% of the assemblies examined.
- organism: E. coli
- assay: whole-genome sequencing
- research focus: variant calling
- approach: experimental assay
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