Oliver Schwengers

Baktfold improves protein functional annotation for microbial genomes using structural information, achieving higher annotation rates than existing tools for bacteria and archaea.

This study analyzes 37970 Streptococcus agalactiae genomes from BakRep to map population trends and identify metadata gaps in serotypes, lineage-specific genes, and AMR profiles.

sORFdb is a database for small proteins and sORFs in bacteria, addressing gaps in detection and functional annotation through curated data and family classification.

BakRep provides a searchable web repository of 661,405 bacterial genomes with consistent characterizations and metadata, enabling flexible querying and offline analysis.

This study uses a mutasynthetic library to identify optimized darobactin derivatives that effectively treat bacterial lung infections in mice.

A uniformly processed set of 2,440,377 bacterial and archaeal genomes with search tools and annotations, plus an AI-mined peptide set yielding ATB20, active in a mouse skin infection model.

Bakta annotates bacterial genomes with one taxon-independent database, uses MD5-hash protein lookups to skip alignments and assign cross-references, detects small proteins, and lowers hypothetical-protein rates versus Prokka/DFAST.

Platon identifies and characterizes plasmid contigs in bacterial draft assemblies using a replicon distribution score, achieving high accuracy and balanced performance across bacterial taxa.

ASA3P automates and scales bacterial genome assembly, annotation, and analysis, enabling rapid processing of hundreds of genomes.

ReferenceSeeker identifies appropriate reference genomes by combining kmer profiling and ANI calculations for microbial genomics analyses.