bioRxivBioengineering
An Open-Source Plate Reader
K. Szymula, M. S. Magaraci, M. Patterson, A. Clark, S. G. Mannickarottu, B. Y. Chow
Abstract
Microplate readers are foundational instruments in experimental biology and bioengineering that enable multiplexed spectrophotometric measurements. To enhance their accessibility, we here report the design, construction, validation, and benchmarking of an open-source microplate reader. The system features full-spectrum absorbance and fluorescence emission detection, in situ optogenetic stimulation, and stand-alone touch screen programming of automated assay protocols. The total system costs \nView larger version (30K):\norg.highwire.dtl.DTLVardef@c26eaborg.highwire.dtl.DTLVardef@efb695org.highwire.dtl.DTLVardef@1bc2f41org.highwire.dtl.DTLVardef@1c25c79_HPS_FORMAT_FIGEXP M_FIG C_FIG
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