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NAR Genomics and BioinformaticsBioinformaticsPeer-reviewed journal article

Pymportx: Facilitating Next-Generation Transcriptomics Analysis in Python

Paula Pena González, Dafne Lozano-ParedesiD, José Luis Rojo‐ÁlvareziD, Luis Bote-CurieliD, Victor Javier Sanchez-Arevalo LoboiD

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Abstract

The efficient importation of quantified gene expression data is pivotal in transcriptomics. Historically, the R package Tximport addressed this need by enabling seamless data integration from various quantification tools. However, the Python community lacked a corresponding tool, restricting cross-platform bioinformatics interoperability. We introduce Pymportx, a Python adaptation of Tximport, which replicates and extends the original packages functionalities. Pymportx maintains the integrity and accuracy of gene expression data while improving processing speed and integration within the Python ecosystem. It supports new data formats and includes tools for enhanced data exploration and analysis. Available under the MIT license, Pymportx integrates smoothly with Pythons bioinformatics tools, facilitating a unified and efficient workflow across the R and Python ecosystems. This advancement not only broadens access to Pythons extensive toolset but also fosters interdisciplinary collaboration and the development of cutting-edge bioinformatics analyses. Availability and ImplementationPymportx is released as an open-source software under the MIT license. The source code is available on GitHub at https://github.com/victorsanchezarevalo/Pymportx.

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