bioRxivBioengineeringPreprint
Non-invasive, Real-time Detection of Vascular Disorders in Mice using Bright SWIR-emitting Gold Nanoclusters and Monte Carlo Image Analysis
Z. Yu, B. Musnier, M. Henry, K. D. Wegner, B. Chovelon, A. Desroches-Castan, A. Fertin, U. Resch-Genger, J.-l. Coll, S. Bailly, Y. Usson, V. Josserand, X. Le Guevel
Abstract
We present here a new approach for non-invasive high resolution whole-body vascular imaging in depth by combining water-soluble and bright SWIR-emitting gold nanoclusters revealing an anisotropic surface charge with Monte Carlo image processing of the images. We applied and validated this approach to quantify vessel complexity in transgenic mice presenting vascular disorders.
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- In vivo label-free observation of tumor-related blood vessels in small animals using a newly designed photoacoustic 3D imaging system
Y. Asao, K.-i. Nagae, … T. Yagi·bioRxiv·Nov 9, 2021
- Gold Nanoprisms as Optical Coherence Tomography Contrast Agents in the Second Near Infrared Window for Enhanced Angiography in Live Animals
P. Si, E. Yuan, … A. de la Zerda·bioRxiv·May 16, 2018
- Multi-modal microvascular cerebral blood flow velocity mapping with 14T single-vessel MRI and optical microscopy in the mouse brain
D. R. Miller, X. A. Zhou, … S. Sakadzic·bioRxiv·Nov 7, 2023
- MicroCT-Based Imaging of Microvasculature in Bone and Peri-Implant Tissues
D. Haberthür, O.-Z. Khoma, … R. Hlushchuk·bioRxiv·Mar 8, 2023
- In vivo microvascular flow quantification in the mouse brain using Row-Column Ultrasound Localization Microscopy and directed graph analysis
Adrien Bertolo, Jérémy Ferrier, … Thomas Deffieux·Journal of Cerebral Blood Flow & MetabolismPeer-reviewed·May 6, 2026
- Deep vascular imaging in the eye with flow-enhanced ultrasound
C. Damsgaard, H. Lauridsen·bioRxiv·Jun 4, 2021