Understanding the phase separation characteristics of nucleocapsid protein provides a new therapeutic opportunity against SARS-CoV-2
D. Zhao, W. Xu, X. Zhang, X. Wang, E. Yuan, Y. Xiong, S. Wu, S. Li, N. Wu, T. Tian, X. Feng, H. Shu, P. Lang, X. Shen, H. Li, , J. Zeng
This study identifies that SARS-CoV-2 nucleocapsid protein undergoes phase separation, which can be modulated by small molecules, offering new therapeutic strategies against COVID-19.
Protein & Cell · Mar 26, 2021Peer-reviewedBiophysics