Topic · Immunology · Immunology and Microbiology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
516 papers
Alexander Yermanos, Victor Greiff, Tanja Stadler…·Sai T. Reddy
This study examines how different computational methods affect the analysis of B cell evolution in murine antibody repertoire sequencing data post-viral infection.
Mark G. Woodcock, Dante S. Bortone, Benjamin Garrett Vincent
STIG generates synthetic T cell receptor sequencing data for evaluating repertoire inference tools using customizable virtual repertoires and simulated sequencing.
Dafni A. Glinos, Blagoje Soskic, Luke Jostins…·Gosia Trynka
Genomic profiling of CD4 T cell activation reveals a sensitivity switch from TCR in naive to CD28 in memory cells.
Mariana Esther Martínez-Sánchez, Leonor Huerta, Elena R Alvarez-Buylla, Carlos Villarreal
The paper extends a Boolean network model of CD4+ T cell differentiation to a continuous model to assess how cytokine concentrations and combinations influence differentiation and plasticity.
Lara Lewis McGrath, Tristan J. Lubinski, J. Carl Barrett, Humphrey Gardner
The paper develops a method to estimate T cell abundance and identify TCR rearrangements from non-targeted DNA sequencing data without prior amplification.
Shinobu Yamamoto, Elizabeth Whalen, Daisuke Chujo…·Damien Chaussabel
The paper develops a systems-based approach to classify T-cell responses using transcriptome data from PBMCs stimulated with peptides, identifying new molecular patterns and transcription factors involved in antigen-specific responses.