Topic · Sensory Systems · Neuroscience

Hearing, Cochlea, Tinnitus, Genetics

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Galectin and Myc enable cochlear progenitor expansion in vitro and in vivo

Marie Kubota, Julia M. Abitbol, Paul K Lee, Maggie S. Matern, Sonia Bustos Barocio, Taha Adnan Jan, Alan Gi-Lun Cheng, Stefan Heller

Single-cell profiling of mouse greater epithelial ridge (GER) organoids points to galectin-1 and Myc as drivers of cochlear progenitor expansion. Myc overexpression also yields organoids from post-hearing-onset cochlear epithelium.

bioRxiv · Sep 24, 2026 · PreprintNeuroscience✦ In-depth digest

Single cell RNA-Seq reveals distinct stem cell populations that drive sensory hair cell regeneration in response to loss of Fgf and Notch signaling

Mark E. Lush, Daniel C. Diaz, Nina Koenecke, Sungmin Baek, Helena Boldt, Madeleine St. Peter, Tatiana Gaitán-Escudero, Andrés Romero‐Carvajal, Elisabeth M. Busch‐Nentwich, Anoja G. Perera, Kathryn Hall, Allison Peak, Jeffrey S. Haug, Tatjana Piotrowski

Single-cell profiling of zebrafish lateral line neuromasts resolves support cell subtypes and lineages, and fgf3 mutant data show Fgf and Notch restrain Wnt-driven proliferation in parallel.

eLife · Jan 25, 2019Peer-reviewedDevelopmental Biology✦ In-depth digest