Elisabeth M. Busch‐Nentwich

The paper shows that EsxA-induced mitochondrial damage in macrophages, combined with hypoxia-driven HIF-1 suppression of respiration, leads to granuloma necrosis and facilitates tuberculosis transmission.

The paper identifies manganese deficiency and neurotoxicity in zebrafish slc39a14 mutants through transcriptome analysis, revealing key molecular pathways involved in manganese homeostasis disruption.

The paper shows that in zebrafish, differentially expressed genes near a mutation may not be caused by the mutation due to allele-specific expression, leading to misinterpretation of RNA-seq results.

The paper identifies Slit3 as a genetic locus influencing nicotine preference in zebrafish and smoking behavior in humans through mutagenesis screens and SNP analysis.

The paper identifies the core gene module required for neural crest induction and reveals the transcriptional basis of genetic compensation via paralogues in zebrafish.

The paper shows that Tcf7l1a is essential for eye field specification in zebrafish but not for eye development, as mutants develop normal eyes through compensatory mechanisms.

Single-cell profiling of zebrafish lateral line neuromasts resolves support cell subtypes and lineages, and fgf3 mutant data show Fgf and Notch restrain Wnt-driven proliferation in parallel.

The paper analyzes mRNA processing in zebrafish mutant lines to explain why few phenotypes are observed despite predicted gene disruptions.

RNA-seq and 3′ end counting over 18 zebrafish stages (1-cell to day 5) profile 23,642 genes; over 100 chromosome 4 zinc finger genes peak at zygotic genome activation.