Anesthesia and Sedative Agents

Anesthesia-induced loss of consciousness disrupts auditory responses beyond primary cortex

This study investigates how anesthesia-induced loss of consciousness affects auditory processing by analyzing intracranial EEG and single-unit activity in patients, finding that higher-order auditory regions show more disruption than primary auditory cortex.

Dynamic changes in rhythmic and arrhythmic neural signatures in the subthalamic nucleus induced by anaesthesia and intubation

This study examines changes in subthalamic nucleus neural activity during anaesthesia and intubation using LFPs and EEG, finding frequency band shifts and coherence changes linked to excitation/inhibition balance.

Continuous regimens of cortico-motor integration calibrate levels of arousal during emergence from anesthesia

The paper identifies cortical and motor activity patterns during emergence from anesthesia in rodents, showing graded regimens of cortico-motor integration that correlate with arousal levels.

Consciousness & Brain Functional Complexity in Propofol Anaesthesia

The paper investigates algorithmic and process complexity measures in functional MRI data from propofol sedation, showing they correlate with sedation levels and support a complexity-based hypothesis of consciousness.

Complexity measures of the electroencephalograph capture loss and recovery of consciousness in patients anesthetized with propofol

This study evaluates nonlinear dynamics analyses of EEG signals to detect loss and recovery of consciousness during propofol anesthesia, finding greater state differences compared to spectral measures.

In search of Universal Cortical Power Changes Linked to NMDA-Antagonist based Anesthetic Induced Reductions in Consciousness.

This study investigates the effects of NMDA-antagonist anesthetics Xe and N2O on cortical power changes using MEG and EEG source imaging, finding distinct frequency-specific patterns.

EEG signal diversity during propofol sedation: an increase in sedated but responsive, a decrease in sedated and unresponsive subjects

The paper investigates EEG signal diversity during propofol sedation, finding increased diversity in responsive subjects and decreased diversity in unresponsive subjects, suggesting EEG diversity as an indirect index of consciousness.

Faster emergence behavior from ketamine/xylazine anesthesia with atipamezole versus yohimbine

This study compares the effects of two adrenoreceptor antagonists on reversing ketamine/xylazine anesthesia in mice, finding that atipamezole accelerates certain emergence behaviors more effectively than yohimbine.

Identifying neurophysiological features associated with anesthetic state in newborn mice and humans

The paper uses machine learning to identify electrophysiological features predicting anesthetic depth in newborn mice and human neonates using EEG and intracranial recordings.

Electroencephalographic markers of brain development during sevoflurane anesthesia in children aged 0 to 3 years old

This study identifies age-related changes in electroencephalographic oscillations during sevoflurane anesthesia in children, revealing developmental milestones in GABAergic circuit activity.

Evidence that loss of consciousness under anesthesia is not associated with impaired stimulus representation in auditory cortex

This study investigates whether anesthetics impair stimulus representation in auditory cortex by analyzing mutual information in rats, finding no consistent impairment across different anesthetic agents.