Emery N. Brown

This study identifies and characterizes fifteen subnetworks within subcortical brain regions, revealing their functional organization and potential applications in understanding neuropsychiatric disorders.

This paper introduces a 3D CNN with a trainable CWT layer and BiCL pre-training for sub-second seizure detection, achieving >95% accuracy on EEG data.

This study uses control-theoretic methods to show that propofol anesthesia reduces interareal control in the brain, leading to a directional breakdown of cortical control.

This paper introduces a Bayesian state-space model to jointly infer oscillatory dynamics and spike-field coupling, showing improved frequency-specific estimates compared to classical methods.

The paper shows that different anesthetics destabilize neural dynamics similarly, affecting recovery and low-frequency power, and linking this to unconsciousness.

This study shows that ketamine and dexmedetomidine induce similar cortical phase alignment patterns in nonhuman primates, suggesting a common mechanism for loss of responsiveness.

This study investigates how propofol-induced loss of consciousness affects neural oscillations and spiking activity in monkeys during auditory processing, finding disrupted alpha/beta inhibition and enhanced gamma/spiking.

This study reports that CT-DBS in awake mice can induce SWDs at low currents during titration, highlighting the need for EEG monitoring.

This study uses DeLASE to show that propofol anesthesia reduces dynamic stability in macaque cortex, mirroring destabilized linear systems.

This study shows how ketamine's effects on NMDA receptor kinetics lead to oscillatory brain dynamics observed in EEG and local field potential recordings.

The paper discusses findings on 40 Hz sensory stimulation's effects on the brain, supporting its potential benefits while noting technical limitations in amyloid burden studies.

This study shows propofol disrupts sensory signal progression through the cortical hierarchy by affecting both Up and Down states, with persistent responses only in auditory cortex.

The paper demonstrates the use of multifunctional fibers to record and modulate neural activity in macaques during cognitive tasks, showing changes in neural activity with local inhibition.

The paper maps brainstem connections sustaining wakefulness using ex vivo diffusion MRI, immunohistochemistry, and in vivo 7 Tesla functional MRI.

This paper constructs a biophysical thalamocortical model to simulate propofol-induced EEG changes, revealing two dynamic states linked to cortical synchronization and brainstem influence.

The paper shows propofol causes alpha rhythms to shift from posterior to anterior in two distinct thalamocortical networks, disrupting sensory and cognitive function during loss of consciousness.

This study uses a biophysical model to show how deep brain stimulation (DBS) of the subthalamic nucleus can restore normal striatal rhythms in Parkinson's disease by modulating fast spiking interneurons and cortical noise.

This study examines ketamine-induced brain dynamics in humans using intracranial recordings, identifying oscillatory changes linked to antidepressant and dissociative effects.

This study examines how propofol anesthesia affects cortical traveling waves in non-human primates, finding increased slow-delta waves and decreased higher-frequency waves during loss of consciousness.

This paper develops an unsupervised machine learning framework to remove surgical artifacts from EDA data in clinical settings, achieving high sensitivity and specificity.

This study assesses the relationship between behavioral and autonomic dynamics during propofol-induced unconsciousness using statistical models and physiological data from nine volunteers.

The paper models EDA pulse amplitudes as differences of inverse Gaussian distributions, showing they outperform other models in describing physiological sweat production.

This study investigates how propofol induces unconsciousness in non-human primates and how thalamic stimulation reverses its effects by altering neural activity patterns.

This paper introduces a robust point-process Granger causality method that accounts for exogenous temporal modulations and trial-by-trial variability in spike trains, improving accuracy in detecting causal relationships between neurons.

The paper analyzes electrodermal activity (EDA) using probability models to characterize its temporal structure and validate them with experimental data.

The paper investigates broadband slow-wave modulation in posterior and anterior cortex during propofol-induced unconsciousness, finding distinct brain state shifts associated with different depths of anesthesia.

The paper introduces a new framework for analyzing neural synchrony across brain regions using state-space coherence, applied to study task-related neural activity in a Stroop task.

This study identifies neural signatures of unconsciousness and shows that thalamic stimulation can reverse these features in anesthetized non-human primates.

The paper investigates how saccadic eye movements influence cortical activity during a word recognition task, finding left-lateralized effects beyond visual stimulation alone.

This study identifies age-related changes in electroencephalographic oscillations during sevoflurane anesthesia in children, revealing developmental milestones in GABAergic circuit activity.