Amit Marmelshtein

An early surge of norepinephrine along brainstem pathways drives sensory-evoked awakening

This study identifies an early surge of norepinephrine in the pontine reticular nucleus as critical for sensory-evoked awakening, revealing circuit-specific roles of the locus coeruleus.

Abrupt and gradual changes in neuronal processing upon falling asleep and awakening

The paper investigates abrupt and gradual changes in neuronal processing during sleep onset and awakening in rats, finding abrupt increases in silent periods and gradual increases in population synchrony.

Sleep-like changes in neural processing emerge during sleep deprivation in early auditory cortex

The paper investigates how sleep deprivation affects neural processing in rat auditory cortex, finding sleep-like changes such as increased population synchrony and silent periods.

Impaired top-down auditory processing despite extensive single-neuron responses during human sleep

The paper investigates auditory processing during sleep using human epilepsy patients' recordings, finding robust neural responses despite reduced alpha-beta power, suggesting impaired top-down processing.

Propofol Anesthesia Concentration Rather Than Abrupt Behavioral Unresponsiveness Linearly Degrades Responses in the Rat Primary Auditory Cortex

This study shows that propofol anesthesia concentration, not abrupt behavioral changes, linearly degrades auditory cortex responses in rats.

Anesthesia-induced loss of consciousness disrupts auditory responses beyond primary cortex

This study investigates how anesthesia-induced loss of consciousness affects auditory processing by analyzing intracranial EEG and single-unit activity in patients, finding that higher-order auditory regions show more disruption than primary auditory cortex.

Local Targeted Memory Reactivation in Human Sleep

This study shows that targeted memory reactivation during sleep improves memory for specific words associated with local brain activity, modulating slow wave activity in the cued hemisphere.