Management of Mendelian Traits in Breeding Programs by Gene Editing: A Simulation Study
This study simulates how gene editing impacts dairy cattle breeding programs by reducing harmful allele frequencies and inbreeding.
Topic · Genetics · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
996 papers
This study simulates how gene editing impacts dairy cattle breeding programs by reducing harmful allele frequencies and inbreeding.
Carolina Garcia-Baccino, Andrés Legarra, Ole Fredslund Christensen…·R. J. C. Cantet
This paper introduces metafounders as pseudo-individuals to reduce bias in genomic evaluations by incorporating ancestral relationships estimated from marker genotypes and pedigrees.
Hubert Pausch, Iona M. MacLeod, Ruedi Fries…·Michael Edward Goddard
This study evaluates imputation accuracy in cattle and identifies QTL for milk fat percentage using imputed variants.
Bruce Moran, Stephen T. Butler, Christopher J. Creevey
The paper compares mutation calling from whole exome and RNA sequencing data in lactating Holstein cows, finding RNAseq can serve as a proxy for exome sequencing with some limitations.
Yanjun Zan, Zheya Sheng, Lars Rönnegård…·Örjan Carlborg
The paper investigates the genetic architecture of long-term selection responses in Virginia chicken lines, identifying multiple loci and genetic mechanisms contributing to body weight variation.