Topic · Molecular Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
454 papers
Bryan L. Roth, Yusuke Gotoh, Patrick M. Giguère, David E. Nichols
The paper introduces GA-PAIR, a chemogenetic platform that enables precise spatio-temporal control of β-arrestin signaling in GPCRs using ABA-induced protein interactions.
bioRxiv · Jan 22, 2018 · PreprintSynthetic Biology
Ricardo Márquez-Gómez, Meridith T. Robins, Citlaly Gutiérrez-Rodelo, Juan Manuel Arias, Jesús Alberto Olivares-Reyes, Richard M. van Rijn, José‐Antonio Arias‐Montaño
The paper investigates functional interactions between histamine H3 and adenosine A2A receptors in rat striatum, showing they form heteromers that modulate synaptic transmission.
Pharmacological Research · Dec 5, 2017Peer-reviewedNeuroscience
Po‐Kuan Chao, Yi‐Yu Ke, Hsiao-Fu Chang, Yihan Huang, Li-Chin Ou, Jian‐Ying Chuang, Yen‐Chang Lin, Pin-Tse Lee, Wan‐Ting Chang, Shuchun Chen, Shau‐Hua Ueng, John Tsu‐An Hsu, Pao‐Luh Tao, Ping‐Yee Law, Horace H. Loh, , Shiu-Hwa Yeh
This study identifies cardiotonic steroids as positive allosteric modulators of MOR that enhance morphine-induced endocytosis and reduce tolerance in pain models.
bioRxiv · Aug 29, 2017 · PreprintNeuroscience
Limin Hao, Yong‐Guang Tong, Kristin Harrington, Jessica L. O’Neill, Afsaneh Sheikholeslami, Xin Wang, Jonathan H. Freedman, Bruce M. Cohen, Edgar A. Buttner
This study identifies Gαq as a mediator of clozapine effects in C. elegans by showing that mutations in dopamine receptors and Gq proteins alter clozapine susceptibility and developmental outcomes.
bioRxiv · Jan 24, 2017 · PreprintGenetics