Author

Jian‐Ying Chuang

National Health Research InstitutesORCID 0000-0001-5124-0643Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Artur KaniaiD· 1 shared Chuan Shih· 1 shared Horace H. LohiD· 1 shared Hsiao-Fu Chang· 1 shared John Tsu‐An Hsu· 1 shared Keefer Lin· 1 shared Li-Chin Ou· 1 shared Ming‐Yuan ChangiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Artur KaniaORCID

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2 papers

Recent·Most cited

Specificity Protein 1 is essential for the limb trajectory of ephrin-mediated spinal motor axons

Pinwen Liao, Ming‐Yuan Chang, Wen-Bin Yang, Keefer Lin, Yi‐Chao Lee, Jian‐Ying Chuang, Yi‐Hsin Wu, Artur Kania, Wen‐Chang Chang, Tsung‐I Hsu, Tzu‐Jen Kao

This study shows that Sp1 regulates ephrin expression in LMC neurons, affecting axon guidance through cis-attenuation and trans-signaling.

bioRxiv · Jan 7, 2025 · PreprintNeuroscience

Drug discovery to counteract antinociceptive tolerance with mu-opioid receptor endocytosis

Po‐Kuan Chao, Yi‐Yu Ke, Hsiao-Fu Chang, Yihan Huang, Li-Chin Ou, Jian‐Ying Chuang, Yen‐Chang Lin, Pin-Tse Lee, Wan‐Ting Chang, Shuchun Chen, Shau‐Hua Ueng, John Tsu‐An Hsu, Pao‐Luh Tao, Ping‐Yee Law, Horace H. Loh, , Shiu-Hwa Yeh

This study identifies cardiotonic steroids as positive allosteric modulators of MOR that enhance morphine-induced endocytosis and reduce tolerance in pain models.

bioRxiv · Aug 29, 2017 · PreprintNeuroscience