Nail Diseases and Treatments

Tipping the lipid scale: Sebaceous fatty acid ratios govern Malassezia antifungal susceptibility

The paper shows that host sebum fatty acid ratios influence Malassezia antifungal susceptibility, with palmitic acid counteracting oleic acid's antagonistic effect.

Rapid and Specific Identification of Emerging Trichophyton mentagrophytes Genotype VII Using an In-House Developed and Validated Real-Time PCR Assay

This paper develops a real-time PCR assay for rapid and specific identification of Trichophyton mentagrophytes genotype VII with high sensitivity and specificity.

Malassezia and the Asian menopausal skin

This study investigates how menopause alters Malassezia fungal populations on skin and their impact on inflammation and skin health in Asian women.

Fourier transform infrared spectroscopy reveals high intraspecies diversity of Malassezia pachydermatis in dogs with atopic dermatitis

This study uses FTIR spectroscopy and WGS to show increased strain diversity of Malassezia pachydermatis in dogs with atopic dermatitis, with specific phylogroups enriched in affected animals.

Fourier transform infrared spectroscopy enables rapid species discrimination across Malassezia and strain-level typing in M. pachydermatis

This study uses Fourier transform infrared spectroscopy to rapidly distinguish Malassezia species and resolve strain-level typing in M. pachydermatis, matching whole-genome sequencing results.

Resolving phylogenetic relationships within the Trichophyton mentagrophytes complex: a RADseq genomic approach challenges status of "terbinafine-resistant" Trichophyton indotineae as distinct species

This paper uses RADseq to analyze 95 isolates of the Trichophyton mentagrophytes complex, revealing that T. indotineae is not genetically distinct enough from T. mentagrophytes to warrant species status, suggesting a reclassification.

Exploring Microbial Dynamics: The Role of Commensals in Healthy and Dandruff-Affected Scalps

This study compares microbial communities on healthy and dandruff-affected scalps, identifying shifts in bacterial and fungal phyla associated with dandruff.

Limited genetic diversity among Malassezia furfur isolates during two one-year neonatal and pediatric bloodstream infection surveys confirms preference for one specific IGS1 genotype in deep-seated infections

Genomic epidemiology of emerging terbinafine-resistant Trichophyton indotineae

The paper identifies terbinafine-resistant Trichophyton indotineae isolates globally, finds high genetic similarity and resistance linked to SQLE mutations, and suggests alternative resistance mechanisms.

Decoding scalp health and microbiome dysbiosis in dandruff

The paper investigates the scalp microbiome in healthy individuals and those with dandruff, identifying propionic acid's role in microbiome balance and its implications for scalp health.

Whole genome analysis illustrates global clonal population structure of the ubiquitous dermatophyte pathogen Trichophyton rubrum

The paper analyzes genome sequences of Trichophyton rubrum and Trichophyton interdigitale to show that T. rubrum is clonal with limited genetic variation and no evidence of sexual reproduction.