R. Blake Billmyre

This study constructs a pangenome of Cryptococcus neoformans, revealing subtelomeres as hotspots for gene content variation and suggesting horizontal gene transfer.

The paper investigates how pericentromeric repeat copy number affects chromosome segregation and gene expression in fission yeast by analyzing natural variation and engineered strains.

This paper uses saturation transposon mutagenesis to identify essential genes and drug resistance mechanisms in Cryptococcus neoformans.

CryptoCEN, a co-expression network for Cryptococcus neoformans, identifies 13 novel DNA damage repair genes with 100% predictive accuracy.

This paper identifies 532 genes involved in sexual reproduction in fission yeast using transposon-insertion sequencing, including 200 previously uncharacterized genes with vertebrate orthologs.

This study identifies genetic pathways in Cryptococcus neoformans that contribute to tolerance of the antifungal drug caspofungin.

The paper maps meiotic recombination in Cryptococcus deneoformans, finding lower recombination rates in unisexual reproduction compared to bisexual crosses.

The paper analyzes genome sequences of Trichophyton rubrum and Trichophyton interdigitale to show that T. rubrum is clonal with limited genetic variation and no evidence of sexual reproduction.

The paper identifies a hypermutator lineage in Cryptococcus deuterogattii caused by an MSH2 mutation, leading to increased mutation rates and drug resistance.